Yellowing of skin sparing the sclerae is indicative of carotenoderma which occurs in healthy individuals who consume excessive carotene-rich foods.Ĭopyright © 2022, StatPearls Publishing LLC. Icterus acts as an essential clinical indicator for liver disease, apart from various other insults. With further increase in serum bilirubin levels, the skin will progressively discolor ranging from lemon yellow to apple green, especially if the process is long-standing the green color is due to biliverdin.īilirubin has two components: unconjugated(indirect) and conjugated(direct), and hence elevation of any of these can result in jaundice. Bilirubin is a yellowish compound formed when old or damaged red blood cells break down. ![]() ![]() Jaundice can be a sign of a serious condition, such as liver disease. This condition happens when there is a high level of bilirubin in the blood. Investigations After youve carried out your physical examination you may need to order investigation tests to confirm your diagnosis or rule out some. Sclerae have a high affinity for bilirubin due to their high elastin content. Yellowish skin is usually caused by jaundice. A yellow tinge to the skin and the whites of the eyes, Splenomegaly is suggestive of parenchymal liver disease or haemolytic jaundice. The normal serum levels of bilirubin are less than 1mg/dl however, the clinical presentation of jaundice as scleral icterus (peripheral yellowing of the eye sclera), is best appreciated only when the levels reach more than 3 mg/dl. Jaundice is a condition in which the bilirubin circulating in your blood is increased, often causing your skin and the whites of your eyes to appear yellow. Deposition of bilirubin happens only when there is an excess of bilirubin, a sign of increased production or impaired excretion. Jaundice, also known as hyperbilirubinemia, is a yellow discoloration of the body tissue resulting from the accumulation of an excess of bilirubin.
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